RMPP vs boox note air 4c

I am a medical student, and I read and annotate a lot of PDF books while taking notes. Currently, I have a 2-in-1 Windows laptop with a digital pen, but I am considering an e-ink device, mainly due to eye strain concerns (occasional 8-hour study sessions).

Both devices seem to be quite similar in many aspects, such as battery life, screen quality, and subjective writing experience. I like the larger size of the RMPP, but I have concerns about its locked-down ecosystem and poor backlight quality.

I would appreciate it if someone with experience using these devices could shed some light on what else I should consider.