Shows like From?

Aside from Lost, are there any shows people would recommend with a similar vibe to From? I'm thinking strange mystery, fairly big cast, it's okay if it's convoluted honestly I just love shows that leave you wondering what's reaaally going on!

Edit: I was gone for an hour and now there's 36 comments, thanks everyone for the suggestions!

Edit #2: I am never going to run out of tv shows to watch!